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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T20884 | Hydroxyzine | Hydroxyzine free base | Histamine Receptor |
Hydroxyzine (Hydroxyzine free base) is an antagonist of histamine H1-receptor. | |||
T8318 | BNC210 | H-Ile-Trp-OH,IW-2143 | AChR |
BNC210 (IW-2143) is a α7 nAChR negative allosteric modulator. BNC210 has potent activity in animal models of anxiety and depression. | |||
T22994 | ML 154 | Neuropeptide Y Receptor | |
neuropeptide S receptor (NPSR) antagonist | |||
T7061 | Duloxetine | Serotonin Transporter | |
Duloxetine is an inhibitor of serotonin-norepinephrine reuptake(Ki of 4.6 nM),with treatment of major depressive disorder and generalized anxiety disorder. | |||
T2200 | Hydroxyzine dihydrochloride | Hydroxyzine 2HCl | Histamine Receptor |
Hydroxyzine dihydrochloride (Hydroxyzine 2HCl) is a histamine H1 receptor antagonist that is effective in the treatment of chronic urticaria, dermatitis, and histamine-mediated pruritus. Unlike its major metabolite CETIR... | |||
T2710 | TCS 1102 | OX Receptor | |
TCS 1102 is an effective, dual orexin receptor antagonist (Ki: 0.2/3 nM for OX2/1 receptors). | |||
T1471 | Duloxetine hydrochloride | Duloxetine HCl,LY-248686 hydrochloride,(S)-Duloxetine hydrochloride,LY-248686 HCl | Dopamine Receptor , 5-HT Receptor , Serotonin Transporter , Norepinephrine |
Duloxetine hydrochloride ((S)-Duloxetine hydrochloride) is a thiophene derivative and selective neurotransmitter uptake inhibitor for SEROTONIN and NORADRENALINE (SNRI). It is an ANTIDEPRESSIVE AGENT and ANXIOLYTIC and i... | |||
T28270 | Osemozotan HCl | Osemozotan hydrochloride,MN-305,MCI-242,MKC-242,MKC242,MCI242 | |
Osemozotan is a 5-HT1A receptor agonist potentially for the treatment of generalized anxiety disorder. | |||
T22453 | Venlafaxine | Wy 45030 | Serotonin Transporter |
Venlafaxine (Wy 45030), an arylalkanolamine serotonin-norepinephrine reuptake inhibitor (SNRI), is used to treat major generalised anxiety disorder (GAD), depressive disorder (MDD), panic disorder and social phobia. | |||
T7136 | AZD-6280 | GABA Receptor | |
AZD6280 is a novel, subtype-selective GABAAα2/3 receptor positive modulators, used for treatment of generalized anxiety disorder. | |||
T2132 | Buspirone hydrochloride | Buspirone HCl,Narol,Buspar | Dopamine Receptor , 5-HT Receptor |
Buspirone hydrochloride (Buspar) is a 5HT(1A) receptor agonist, used to treat generalized anxiety disorder (GAD). | |||
T68172 | Zalospirone | 5-HT Receptor | |
Zalospirone is a 5-HT1A receptor agonist that can be used to study anxiety disorders and major depressive disorder. | |||
T22442 | Trazodone | AF-1161 | 5-HT Receptor |
Trazodone (AF-1161), a 5-HT 2A/2C receptor antagonist, is used as an antidepressant for treating major anxiety disorders and depressive disorder. | |||
T26915 | BTG-1640 | ABIO-0801,ABIO-08-01,SP-1640 | |
BTG-1640 is used potentially for the treatment of anxiety and panic disorder. | |||
T1885L | Siramesine Fumarate | LU-28179,LU-28-179,LU 28 179 | |
Siramesine Fumarate, a sigma receptor agonist, is used potentially for the treatment of generalized anxiety disorder. | |||
T68683 | Sertraline Free Base | ||
Sertraline Free Base is a Selective Serotonin Reuptake Inhibitor (SSRI). It can treat depression, obsessive-compulsive disorder (OCD), posttraumatic stress disorder (PTSD), premenstrual dysphoric disorder (PMDD), social ... | |||
T69063 | Orvepitant | ||
Orvepitant is a potent and selective NK1 antagonist, which may be potentially useful for patients with major depressive disorder (MDD), anxiety and insomnia. | |||
T68579 | Fluvoxamine acid | ||
Fluvoxamine acid is a medication which functions as a selective serotonin reuptake inhibitor (SSRI) and σ1 receptor agonist. Fluvoxamine is used primarily for the treatment of obsessive-compulsive disorder (OCD), and is ... | |||
T11113 | Duloxetine D3 hydrochloride | (S)-Duloxetine D3 hydrochloride,LY248686 D3 hydrochloride | Others |
Duloxetine D3 hydrochloride is a serotonin-norepinephrine reuptake inhibitor (SNRI) with a Ki of 4.6 nM, used for treatment of major depressive disorder and generalized anxiety disorder (GAD).Duloxetine D3 hydrochloride ... | |||
T61376 | Opipramol | ||
Opipramol (Ensidon) is an atypical tricyclic antidepressant (TCA) that primarily acts as a sigma (σ) receptor agonist, exhibiting potent interaction with sigma recognition sites (K i value of 50 nM). It can be employed i... |